Expert Tips and Interviews on Living with Parkinson's Disease
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Michael Okun Indu Subramanian Jonny Acheson

 

Treat Bothersome Parkinson's Disease Hallucinations

If you have hallucinations and psychosis in the setting of Parkinson’s disease and it is bothersome to you or to your family members here are a few useful tips:

  • Check for a urinary tract infection
  • Make sure there is no pneumonia or other infection
  • Medications may be the cause especially pain medications, muscle relaxants, and benzodiazepines 
  • Temporary reduction in Parkinson’s treatment medication dosages may help but may also worsen Parkinson symptoms
  • In some cases stopping anticholinergics (trihexyphenidyl, artane, beztropine, benadryl), amantadine, MAO-B inhibitors (selegiline, rasagiline, zelapar, others), entacapone, and even dopamine agonists may be helpful
  • Small doses of sinemet or madopar can beused to try to gain control of the hallucinations/psychosis, as small doses may be less likely to result in hallucinations
  • Dopamine blocking medications such as seroquel (Quetiapine) or clozaril (Clozapine) are the best medications in Parkinson's disease
  • Other dopamine blockers such as haldol, resperidal, and olanzapine may worsen Parkinson’s symptoms and are rarely used
  • It is important to see the doctor immediately for treatment of hallucinations
  • In some cases the hallucinations are not bothersome and will not require treatment
Michael Okun