Parkinsonsecrets.com and Parkinsonbreakthrough.com blogs are the Official Website for the books:  Parkinson's Treatment: 10 Secrets to a Happier Life and 10 Breakthrough Therapies for Parkinson's Disease.

Dr. Okun is the co-founder of the University of Florida Center for Movement Disorders and Neurorestoration, the National Medical Director for the National Parkinson Foundation, as well as the author of several books including Ask the Expert about Parkinson's Disease, Lessons from the Bedside, 10 Breakthrough Therapies for Parkinson's Disease and Parkinson's Treatment: 10 Secrets to a Happier life due out in 2013.  His secrets book was translated into 20 languages so that it can be made available to Parkinson's disease sufferers around the world.  Dr. Okun has been recently been honored at the White House as a Champion of Change for Parkinson's Disease. Dr. Okun has been published in journals such as the New England Journal of Medicine and people travel from around the world to seek his opinion on best treatment approaches for this disease.

What you need to know about creatine in Parkinson's now that NIH trial is reported negative

- The NET-PD LS-1 study was started in around 2007 in an effort to identify a potential disease modifying or symptomatic effect of creatine.

 - The study was stopped last week after an interim analysis revealed that it was unlikely that creatine would reveal a benefit for Parkinson’s disease. 

 - Creatine has its effects on the mitochondria (the part of the cells in the body known as the energy producing region)

- Creatine is also known to be an anti-oxidant

- Though the study did not meet criteria as “positive” for a symptomatic or disease modifying benefit, the investigators have amassed one of the largest longitudinal research datasets in history for a Parkinson’s disease trial.  There were over 1700 participants and the fact that they were followed long-term will bring a lot of important data to the field.

- There were (are) no safety concerns with creatine.

- There is no need to panic about whether to continue or to stop.  Just see your doctor and have a frank discussion. 

 - We should not forget that there was a randomized trial of creatine with resistance training that showed a benefit in Parkinson's disease.

- Here is the official statement from NINDS on the creatine results.