Parkinsonsecrets.com and Parkinsonbreakthrough.com blogs are the Official Website for the books:  Parkinson's Treatment: 10 Secrets to a Happier Life and 10 Breakthrough Therapies for Parkinson's Disease.

Dr. Okun is the co-founder of the University of Florida Center for Movement Disorders and Neurorestoration, the National Medical Director for the National Parkinson Foundation, as well as the author of several books including Ask the Expert about Parkinson's Disease, Lessons from the Bedside, 10 Breakthrough Therapies for Parkinson's Disease and Parkinson's Treatment: 10 Secrets to a Happier life due out in 2013.  His secrets book was translated into 20 languages so that it can be made available to Parkinson's disease sufferers around the world.  Dr. Okun has been recently been honored at the White House as a Champion of Change for Parkinson's Disease. Dr. Okun has been published in journals such as the New England Journal of Medicine and people travel from around the world to seek his opinion on best treatment approaches for this disease.

Neurturin, GDNF, and Trophic Factors as Treatments for Parkinson's Disease

-Gene therapies and trophic factors are potential treatments under development for Parkinson’s disease

-Trophic factors are proteins that are important to cell development and brain cell survival  

-Glial cell derived neurotrophic factor (GDNF) was placed into Parkinson’s disease brains but found to be ineffective and to have some worrisome adverse events

-Another trophic factor, a pill called Cogane, also failed a human trial

-CERE-120 or neurturin was yet another trophic factor that was recently announced to have failed clinical trials

-Though these early trophic factor trials have been disappointing, they have demonstrated the safety of using adeno-associated gene therapy in human patients and that is very exciting

-One of the keys to the successful use of trophic factors and other therapies is in developing a strategy to beat the brain's protective layer- the blood-brain barrier

-The most common trophic factor treatment for Parkinson's disease is simple exercise which stimulates the brain's native trophic factors

Read more about trophic factor treatment and Parkinson's disease at Dr. Okun's What's Hot in Parkinson's disease blog (NPF) or at Parkinson's Secrets